08/04/2025
In 2007, Mark Miller was diagnosed with PTSD. The military put him on fluoxetine, otherwise known as Prozac. He became suicidal.
Miller eventually weaned himself off medications and used “neuroplasticity” therapy which forms new connections in the brain.
This April, returning suicidal thoughts prompted Miller to visit a Department of Veterans Affairs hospital in San Antonio. A nurse practitioner prescribed a powerful antipsychotic in a five-minute appointment.
Six days later, Miller returned, stepped off a shuttle bus and fatally shot himself in the head. “He did it clearly to speak for all the veterans who have no voice,” his father said.
Hundreds of thousands of veterans with PTSD have been prescribed simultaneous doses of powerful psychiatric drugs. The practice, known as “polypharmacy,” can tranquilize patients to the point of numbness, cause weight gain and increase suicidal thoughts when it involves pharmaceuticals that target the central nervous system, according to scientific studies and veterans’ accounts.
The VA’s own guidelines say no data support drug combinations to treat PTSD. The Food and Drug Administration warns that combining certain medications such as opioids and benzodiazepines can cause serious side effects, including death.
Nonetheless, prescribing cocktails of such drugs is one of the VA’s most common treatments for veterans with PTSD, and the number of veterans on multiple psychiatric drugs is a growing concern at the agency, according to interviews with more than 50 veterans, VA health practitioners, researchers and former officials, and a review of VA medical records and studies.
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