30/05/2026
Paracelsus the physician, alchemist and philosopher born in Switzerland in 1493, is often called the father of toxicology.
His famous principle,
"The dose makes the poison,"
tells us that any substance can be harmful—or beneficial—depending on how much is taken.
Salt is a good example of Paracelsus's principle. Approximately 1–2 g per kilo of bodyweight is potentially lethal. So even a substance essential for life can become a poison when the dose is high enough.
This idea remains the foundation of modern toxicology today.
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